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Patient education should address both the expected benefits and potential adverse effects of semaglutide, with particular emphasis on gastrointestinal symptoms that may be difficult to distinguish from autoimmune disease manifestations
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A muscle-preserving GLP-1 plan should include: Protein at each meal Resistance training at least several days per week when medically appropriate Walking or low-impact movement Hydration and electrolyte support when needed Adequate sleep Monitoring for fatigue or weakness Avoiding overly restrictive dieting Adjusting the medication dose if appetite suppression becomes too strong The goal is not simply to weigh less
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